Metreveli, Nunu and Namicheishvili, L and Jariashvili, K and Chikvaidze , E and Mrevlishvili , G (2005) Collagen photodegradation under UV irradiation. Journal of Biological Physics and Chemistry, 5 (4). pp. 133-136. ISSN 1512-0856
This is the latest version of this item.
Abstract
The influence of UV irradiation on the collagen triple helix has been studied at the molecular level. It is shown that UV irradiation causes the appearance of primer free radicals in the water surrounding the collagen, which then interact with the proline residue of the protein with the appearance of secondary free radicals. This is connected with destabilization of the collagen molecule as the defects in the amino acid residues probably lead to cleavage of the covalent bonds near the damaged sites, so maintaining the triple helical structure. The presence of ascorbic acid (vitamin C) in the solution protects the collagen molecule from the action of the secondary free radicals.
Item Type: | Article |
---|---|
Subjects: | Q Science > QC Physics Q Science > QH Natural history > QH301 Biology |
Divisions: | Institutes > Institute of Biophysics |
Depositing User: | პროფესორი ნუნუ მეტრეველი |
Date Deposited: | 28 Feb 2014 13:39 |
Last Modified: | 21 Apr 2015 09:16 |
URI: | http://eprints.iliauni.edu.ge/id/eprint/1305 |
Available Versions of this Item
-
Collagen photodegradation under UV irradiation. (deposited 18 Feb 2014 06:19)
- Collagen photodegradation under UV irradiation. (deposited 28 Feb 2014 13:39) [Currently Displayed]
Actions (login required)
![]() |
View Item |