259 7 959 1 2935 document 959 Cell Biology International.pdf application/pdf 7ee48d9e0a7a758d00785173221dbaeb MD5 601829 2014-01-20 10:36:45 http://eprints.iliauni.edu.ge/259/1/Cell%20Biology%20International.pdf 259 1 1 application/pdf text ge public

Cell Biology International.pdf

961 2 2947 document 961 lightbox.jpg image/png 3641aee542b6d74a7f99e4336c77b659 MD5 44372 2014-01-20 10:48:24 http://eprints.iliauni.edu.ge/259/3/lightbox.jpg 259 3 3 image/png other Thumbnails conversion from text to thumbnail_lightbox ge public

lightbox.jpg

http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/islightboxThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/959 962 2 2948 document 962 preview.jpg image/png e5d02ca1646d072739167a0346e542bf MD5 17975 2014-01-20 10:48:25 http://eprints.iliauni.edu.ge/259/4/preview.jpg 259 4 4 image/png other Thumbnails conversion from text to thumbnail_preview ge public

preview.jpg

http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/ispreviewThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/959 963 2 2949 document 963 medium.jpg image/png 01293bca9fb7f426bc017335ba5c3845 MD5 6778 2014-01-20 10:48:26 http://eprints.iliauni.edu.ge/259/5/medium.jpg 259 5 5 image/png other Thumbnails conversion from text to thumbnail_medium ge public

medium.jpg

http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/ismediumThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/959 964 2 2950 document 964 small.jpg image/png 7036810f3e2178abb9e5af6b99deb7f5 MD5 1804 2014-01-20 10:48:27 http://eprints.iliauni.edu.ge/259/6/small.jpg 259 6 6 image/png other Thumbnails conversion from text to thumbnail_small ge public

small.jpg

http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/959 http://eprints.org/relation/issmallThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/959 archive 87 disk0/00/00/02/59 2014-01-20 10:47:09 2014-01-20 10:47:09 2014-01-20 10:47:09 article show Cho Won Jin Jeremik Aleksandar Rognlier Kathy T Zhvania Mzia G mzia_zhvania@iliauni.edu.ge Lazrishvili Iliai L Bikashvili Tamar takobikashvili@yahoo.com Jena Bhanu bjena@med.wayne.edu Zhvania Mzia G pub QP ins10 public Neuronal communication is dependent on the fusion of 40e50 nm in diameter synaptic vesicles containing neurotransmitters, at the presynaptic membrane. Here we report for the first time at 5e8 A˚ resolution, the presence of 8e10 nm in diameter cup-shaped neuronal fusion pores or porosomes at the presynaptic membrane, where synaptic vesicles dock and fuse to release neurotransmitters. The structure, isolation, composition, and functional reconstitution of porosomes present at the nerve terminal are described. These findings reveal the molecular mechanism of neurotransmitter release at the presynaptic membrane of nerve terminals. 2004 Cell Biology International 28 Elsevier 699-708 TRUE 1065-6995