253 8 1742 1 5001 document 1742 Neuroscience letters.pdf application/pdf 2a77d50ef20671640c91410714c0071a MD5 104958 2014-01-23 07:34:45 http://eprints.iliauni.edu.ge/253/1/Neuroscience%20letters.pdf 253 1 1 application/pdf text en public

Neuroscience letters.pdf

1743 2 5003 document 1743 lightbox.jpg image/png c74f5087cdc39cbb48ebd77263baa4c0 MD5 47289 2014-01-23 07:35:07 http://eprints.iliauni.edu.ge/253/2/lightbox.jpg 253 2 2 image/png other Thumbnails conversion from text to thumbnail_lightbox ge public

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http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/islightboxThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/1742 1744 2 5004 document 1744 preview.jpg image/png 0856cd38bf4f3ae5ac22f38dedfee671 MD5 19376 2014-01-23 07:35:08 http://eprints.iliauni.edu.ge/253/3/preview.jpg 253 3 3 image/png other Thumbnails conversion from text to thumbnail_preview ge public

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http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/ispreviewThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/1742 1745 2 5005 document 1745 medium.jpg image/png 838b859eeed2ce1e29c777e6a99fe4a7 MD5 7205 2014-01-23 07:35:09 http://eprints.iliauni.edu.ge/253/4/medium.jpg 253 4 4 image/png other Thumbnails conversion from text to thumbnail_medium ge public

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http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/ismediumThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/1742 1746 2 5006 document 1746 small.jpg image/png a745cde9b4bc455d8d7a215c647b48fe MD5 1829 2014-01-23 07:35:10 http://eprints.iliauni.edu.ge/253/5/small.jpg 253 5 5 image/png other Thumbnails conversion from text to thumbnail_small ge public

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http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/1742 http://eprints.org/relation/issmallThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/1742 archive 27 disk0/00/00/02/53 2015-04-07 08:52:43 2015-04-07 08:52:43 2015-04-07 08:52:43 article show Dugladze Tamar Lepsveridze Eka eka_lepsveridze@iliauni.edu.ge Breustedt J. Kehrer C. Heineman Uwe Gloveli Tengiz pub QP fac_med public The information transfer from the superficial layers of the entorhinal cortex (EC) to the hippocampus is regulated in a frequency dependent manner. Phencyclidine and related compounds such as MK-801 produce psychotic symptoms that closely resemble schizophrenia. We studied the effects of systemic administration of MK-801 on the signal transfer from the EC layer III to the hippocampal area CA1. High frequency (above 10 Hz) activation of the bi-synaptic entorhinal input in control animals results in a strong suppression of the field potentials in the stratum lacunosum-moleculare of the area CA1. In contrast, in MK-801 pretreated rats the field response was less reduced. The field potential responses evoked in these two groups of animals by high-frequency activation of the monosynaptic input were similar suggesting selective alterations in layer III of the medial EC. We suggest, that MK-801 causes disinhibition of layer III projection cells and, therefore, may cause strong, pathological activation of direct layer III-CA1 pathway. 2004 published Neurosci Lett. 354 3 185-188 TRUE http://www.sciencedirect.com/science/article/pii/S0304394003011881