1829 7 7692 1 20966 document 7692 Molecular Mechanisms of memory in imprinting.pdf application/pdf e9a8ba2ae3edaf5f90827eb5169c0279 MD5 1189657 2015-03-23 08:12:48 http://eprints.iliauni.edu.ge/1829/1/Molecular%20Mechanisms%20of%20memory%20in%20imprinting.pdf 1829 1 1 application/pdf text ge public

Molecular Mechanisms of memory in imprinting.pdf

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http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/7692 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/7692 http://eprints.org/relation/ismediumThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/7692 7697 2 20975 document 7697 small.jpg image/png eb0ce29fd2fb7b3d37f392355e081643 MD5 1678 2015-03-23 08:23:17 http://eprints.iliauni.edu.ge/1829/6/small.jpg 1829 6 6 image/png other Thumbnails conversion from text to thumbnail_small ge public

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http://eprints.org/relation/isVersionOf http://eprints.iliauni.edu.ge/id/document/7692 http://eprints.org/relation/isVolatileVersionOf http://eprints.iliauni.edu.ge/id/document/7692 http://eprints.org/relation/issmallThumbnailVersionOf http://eprints.iliauni.edu.ge/id/document/7692 archive 110 disk0/00/00/18/29 2015-03-23 10:51:45 2015-03-23 10:51:45 2015-03-23 10:51:45 article show Solomonia Revaz revaz_solomonia@iliauni.edu.ge McCabe BJ pub Neurobiology Q1 ins10 public Abstract Converging evidence implicates the intermediate and medial mesopallium (IMM) of the domestic chick forebrain in memory for a visual imprinting stimulus. During and after imprinting training, neuronal responsiveness in the IMM to the familiar stimulus exhibits a distinct temporal profile, suggesting several memory phases. We discuss the temporal progression of learning-related biochemical changes in the IMM, relative to the start of this electrophysiological profile. c-fos gene expression increases <15min after training onset, followed by a learning-related increase in Fos expression, in neurons immunopositive for GABA, taurine and parvalbumin (not calbindin). Approximately simultaneously or shortly after, there are increases in phosphorylation level of glutamate (AMPA) receptor subunits and in releasable neurotransmitter pools of GABA and taurine. Later, the mean area of spine synapse post-synaptic densities, N-methyl-d-aspartate receptor number and phosphorylation level of further synaptic proteins are elevated. After ∼15h, learning-related changes in amounts of several synaptic proteins are observed. The results indicate progression from transient/labile to trophic synaptic modification, culminating in stable recognition memory. 2015 Neuroscience and Biobehavioural Reviews 50 56-69 TRUE